Auristatin F是细胞毒性分子，微管蛋白修饰分子，强效抗**活性，MMAF的类似物以及在抗体药物偶连体开发中作为毒素分子。
 英文名称：Auristatin F
中文名称：奥瑞他汀 F
CAS：163768-50-1
抗体药物偶联物（Antibody-drug conjugate, ADC）是通过化学键将具有生物活性的细胞毒药物连接到单克隆抗体（mAb）上，单克隆抗体（mAb）作为载体将细胞毒药物靶向运输到目标细胞中发挥作用的一类药物。既具有细胞毒药物杀伤力强大的特点，又结合了重组单克隆抗体（mAb）高度的靶向性，稳定性和有利的药代动力学特征，主要表现为：治疗效力强；特异性高；免疫原性弱，不容易产生抗药性；血清中循环时间长（短于单抗）；对非靶点毒性弱等。

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MC-va-PAB-MMAD
MA-PEG4-VC-PAB-DMAE-PNU159682
MA-PEG4-VA-PBD
MC-vc-PAB-MMAF
MC-vc-PAB-MMAD
MC-vc-PAB-Auristatin 0101
MA-PEG8-VA-PAB-SG3199
CL2A-SN 38
MC-GGFG-DX8951
MEDI4276_linker payload
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DBCO-PEG4-vc-PAB-MMAE
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DBCO-PEG4-vc-PAB-Duocarmycin SA
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