生物活性：Leucomalachite green-d6 is the deuterated derivative of Leucomalachite green (HY-D0300). Leucomalachite green is the major reduced metabolite of malachite green (MG) and has lower cytotoxicity (such as HEp-2 and Caco-2) than malachite green. Leucomalachite green may be involved in interfering with cell metabolism or redox balance and can be used to evaluate its potential harm to human cells as a food contaminant[1][2].
体外研究(In Vitro)：Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
QY千亿国际 has not independently confirmed the accuracy of these methods. They are for reference only.
Leucomalachite green-d6 相关抗体:
Mouse IgG Isotype Control
6X His-tag (C-terminal) Antibody (YA860)
DYKDDDDK Tag (FLAG) Antibody
GFP Antibody
Myc-tag Antibody
HA tag Antibody (YA856)
GST-Tag Antibody HRP Conjugated
V5-tag Antibody
Collagen I alpha 2 Antibody
Rabbit IgG Isotype Control
6X His Tag (C-terminal) Antibody
His Tag Antibody (HRP) (YA877)
HA Tag Antibody (HRP) (YA876)
EYFP Tag Antibody (YA872)
HSV Tag Antibody (YA878)
MBP Tag Antibody (YA879)
RFP Tag Antibody (YA882)
S Tag Antibody (YA883)
SRT Tag Antibody (YA884)
Strep-Tag II Antibody (YA885)
TAP Tag Antibody (YA887)
Collagen II Antibody
Collagen III Antibody
Collagen X Antibody
Collagen IV Antibody
Collagen I Antibody
Collagen VI alpha 1/2/3 Antibody (YA2637)
AmCyan Tag Antibody (YA864)
DsbA Tag Antibody (YA868)
E2 Tag Antibody (YA870)
分子量：336.50
Formula：C23H20D6N2
CAS 号：1173021-13-0
非标记 CAS：129-73-7
运输条件：Room temperature in continental US; may vary elsewhere.
储存方式：Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (534 KB)
产品使用指南 (1538 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-236.
 [Content Brief]
[2]. Ya-hui Li, et al. Development of a group selective molecularly imprinted polymers based solid phase extraction of malachite green from fish water and fish feed samples. Anal Chim Acta. 2008 Aug 29;624(2):317-25.
 [Content Brief]
[3]. Stammati A, et al. Effects of malachite green (MG) and its major metabolite, leucomalachite green (LMG), in two human cell lines. Toxicol In Vitro. 2005 Oct;19(7):853-8.
 [Content Brief]